To open the drops bottle, remove the safety ring, pulling its protruding part until it is fully removed. Then, remove the cap pulling it upwards. Tilt your head slightly to the back, look up and gently pull down your lower eyelid. Holding the bottle with the hole directed downwards, apply 1 drop to the conjunctival sac 3-5 times a day, pressing the bottle hard and long. Close your eyes slowly to allow the fluid to spread evenly on the eye surface. To keep the product sterile, avoid contact of the applicator tip with your eyes or hands. Remove the drop staying in the hole by means of a slight tap at the bottom when the bottle is still turned downwards. Close the bottle, slightly pressing the cap to the hole.